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Distribution of the modal minimum inhibitory concentration (MIC) for omadacycline by reference <t>broth</t> <t>microdilution</t> <t>(BMD)</t> ( A ) and adjudicated MIC distribution by MTS (Liofilchem). ( B ) Adjudicated MIC represents modal MIC, which is the most frequent MIC value observed. Median used in cases without a modal MIC.
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Minimal inhibitory concentrations <t> (MICs) </t> for parental and OXA935 deletion strains
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Distribution of the modal minimum inhibitory concentration (MIC) for omadacycline by reference broth microdilution (BMD) ( A ) and adjudicated MIC distribution by MTS (Liofilchem). ( B ) Adjudicated MIC represents modal MIC, which is the most frequent MIC value observed. Median used in cases without a modal MIC.

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Evaluation of omadacycline in vitro activity against Corynebacterium species

doi: 10.1128/aac.01864-24

Figure Lengend Snippet: Distribution of the modal minimum inhibitory concentration (MIC) for omadacycline by reference broth microdilution (BMD) ( A ) and adjudicated MIC distribution by MTS (Liofilchem). ( B ) Adjudicated MIC represents modal MIC, which is the most frequent MIC value observed. Median used in cases without a modal MIC.

Article Snippet: Isolates were sent out to a reference laboratory (Laboratory Specialists Inc., OH) for MIC testing by BMD, performed in triplicate using CLSI methods ( ).

Techniques: Concentration Assay

Results of  MIC  testing by  BMD  and MTS for omadacycline <xref ref-type= a " width="100%" height="100%">

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Evaluation of omadacycline in vitro activity against Corynebacterium species

doi: 10.1128/aac.01864-24

Figure Lengend Snippet: Results of MIC testing by BMD and MTS for omadacycline a

Article Snippet: Isolates were sent out to a reference laboratory (Laboratory Specialists Inc., OH) for MIC testing by BMD, performed in triplicate using CLSI methods ( ).

Techniques:

Minimal inhibitory concentrations  (MICs)  for parental and OXA935 deletion strains

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family β-Lactamase from Pseudomonas aeruginosa

doi: 10.1128/aac.00985-22

Figure Lengend Snippet: Minimal inhibitory concentrations (MICs) for parental and OXA935 deletion strains

Article Snippet: BMD MICs for amikacin (AMK), meropenem-vaborbactam (MVB), imipenem (IPM), imipenem-relebactam (IMR), cefiderocol (FDC), ceftolozane-tazobactam (C/T), and ceftazidime-avibactam (CZA), were determined using commercially available Sensititre Gram Negative Susceptibility Testing Plates (Thermo Fisher Scientific, catalog number: MDRGN2F) per the manufacturer’s protocol.

Techniques:

 MICs  for PAO1 and PA14 induced to express OXA-10, OXA-14, and OXA-935

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family β-Lactamase from Pseudomonas aeruginosa

doi: 10.1128/aac.00985-22

Figure Lengend Snippet: MICs for PAO1 and PA14 induced to express OXA-10, OXA-14, and OXA-935

Article Snippet: BMD MICs for amikacin (AMK), meropenem-vaborbactam (MVB), imipenem (IPM), imipenem-relebactam (IMR), cefiderocol (FDC), ceftolozane-tazobactam (C/T), and ceftazidime-avibactam (CZA), were determined using commercially available Sensititre Gram Negative Susceptibility Testing Plates (Thermo Fisher Scientific, catalog number: MDRGN2F) per the manufacturer’s protocol.

Techniques:

OXA-14 and OXA-935 induction increase ceftazidime resistance in PAO1 and PA14

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family β-Lactamase from Pseudomonas aeruginosa

doi: 10.1128/aac.00985-22

Figure Lengend Snippet: OXA-14 and OXA-935 induction increase ceftazidime resistance in PAO1 and PA14

Article Snippet: BMD MICs for amikacin (AMK), meropenem-vaborbactam (MVB), imipenem (IPM), imipenem-relebactam (IMR), cefiderocol (FDC), ceftolozane-tazobactam (C/T), and ceftazidime-avibactam (CZA), were determined using commercially available Sensititre Gram Negative Susceptibility Testing Plates (Thermo Fisher Scientific, catalog number: MDRGN2F) per the manufacturer’s protocol.

Techniques: